SNIM (MTN) - Entente Setif (ALG) 1 - 5
Sporting Bissau (GBS) - Olympic Khouribga (MAR)
Tonnerre (BEN) - Africa Sports (CIV) 0 - 0
APR (RWA) - Zamalek (EGY) 1 - 2
Douanes (SEN) - CF Ouagadougou (BUR) 0 - 0
Royal Leopards (SWZ) - Dynamos (ZIM) 0 - 1
Sahel (NIG) - AshantiGold (GHA) 1 - 0
Motema Pembe (COD) - Gombe Utd (NGR) 2 - 0
Vital’O (BDI) - Cotonsport Garoua (CMR) 0 - 1
FC 105 (GAB) - Hearts of Oak (GHA) 3 - 0
Stade Malien (MLI) - Primeiro Agosto (ANG) 1 - 2
Saloum (SEN) - Club Africain (TUN)
ASKO Kara (TOG) - Union Douala (CMR) 3 - 1
Simba (TAN) - Awassa City (ETH) 3 - 0
Platinum Stars (RSA) - Lesotho Correction Services (LES) 4 - 0
Curepipe Starlight (MRI) - Coin Nord Mitsamiouli (COM) 2 - 0
Miembeni (ZAN) - Mamelodi Sundowns (RSA) 0 - 1
Revenue Authority (UGA) - ZESCO Utd (ZAM) 0 - 2